Corynebacterium pseudotuberculosis infection in Saanen×Kilis crossbred (White) goats in Ankara, Turkey and effective kanamycin treatment: A prospective, randomized, double-blinded, placebo-controlled clinical trial

In the present paper we describe Corynebacterium pseudotuberculosis infection in the Saanen×Kilis crossbred goats with abscesses located in retropharyngeal (n = 29), mandibular (n = 49), parotid (n = 26), superficial cervical (n = 40), subiliac (n = 23) and popliteal (n = 11) lymph nodes. The most prominent site of the abscesses was in the anterior half of the body affecting 80.89% of the goats. Histopathological examination of the lymph nodes showed pyogranulomatous inflammation. The goats were randomly assigned to either kanamycin treatment group or a placebo. The efficacy of kanamycin was assessed clinically and on the basis of a lesion score derived from the examination of the affected lymph nodes. Clinical evaluations and lesion scoring were done by the same veterinary investigator. Both owners and the veterinary investigator were blinded to the allocation to the groups. Throughout the study kanamycin treatment significantly decreased (P < 0.05) the investigator’s clinical scores while no significant changes were detected in the placebo group. © 2008 Elsevier B.V. All rights reserved.