Estimation of post-vaccination antibody titre against goat pox and determination of protective antibody titre

Goats maintained in farm/under rural condition by individual owners with definite history of vaccination were vaccinated with Freeze Dried Tissue Culture Goat Pox Vaccine and antibody titre was determined up to 1 year post-vaccination period. A few experimental goats were vaccinated and subsequently challenged with isolated virulent field virus and antibody titre of vaccinated animals observed at different intervals was compared with the antibody titre observed in the experimental goats. Post-vaccination serum neutralizing antibody titre was 1:32 at 1 year post-vaccination. All the vaccinated experimental goats withstood virulent field virus challenge on 21st day with serum neutralizing antibody titre of 1:16.