Author/Authors :
A. C. Jones، نويسنده , , A. P. Sheppard، نويسنده , , R. M. Sok، نويسنده , , C. H. Arns، نويسنده , , A. Limaye، نويسنده , , H. Averdunk، نويسنده , , A. Brandwood، نويسنده , , A. Sakellariou، نويسنده , , T. J. Senden، نويسنده , , B. K. Milthorpe، نويسنده , , M. A. Knackstedt، نويسنده ,
Abstract :
We demonstrate the capability of X-ray micro-computed tomography to image the micro-structure of human cortical bone. At 5 μm voxel size we observe the complex morphology of the Haversian network in three dimensions. The local thickness of Haversian canals is measured using a maximal sphere algorithm and found to have a bimodal signature and a mean radius of 19.2 μm. The intra-cortical porosity due to Haversian canals is measured as 3.0%. Both results are in agreement with traditional histomorphometric measurements. We show that at higher resolutions one can resolve the spatial distribution of lacunae in cortical bone.
