• Title of article

    Lower bounds for optimal alignments of binary sequences

  • Author/Authors

    Cynthia Vinzant، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2009
  • Pages
    6
  • From page
    3341
  • To page
    3346
  • Abstract
    In parametric sequence alignment, optimal alignments of two sequences are computed as a function of matches, mismatches and spaces, producing many different optimal alignments. In the two-parameter case, Gusfield et al shows that the number of distinct optimal alignment summaries for a pair of sequences is image. Here we construct binary sequences of length image with image distinct optimal alignment summaries. This shows that the upper bound given by Gusfield et al. is tight over all alphabets, thereby disproving the “image conjecture”. Thus the maximum number of distinct optimal alignment summaries over all pairs of length image sequences is image.
  • Keywords
    Parametric analysis , Computational biology , sequence alignment
  • Journal title
    Discrete Applied Mathematics
  • Serial Year
    2009
  • Journal title
    Discrete Applied Mathematics
  • Record number

    887270