Title of article :
Investigation ofanewGRASP-basedclusteringalgorithmappliedtobiologicaldata
Author/Authors :
Maria Helena do Nascimento Souza، نويسنده , , FranklinaM.B.Toledo، نويسنده , , AndréC.P.L.F.deCarvalho، نويسنده ,
Issue Information :
ماهنامه با شماره پیاپی سال 2010
Abstract :
A largeamountofbiologicaldatahasbeenproducedinthelastyears.Importantknowledgecanbe
extracted fromthesedatabytheuseofdataanalysistechniques.Clusteringplaysanimportantrolein
data analysis,byorganizingsimilarobjectsfromadatasetintomeaningfulgroups.Severalclustering
algorithms havebeenproposedintheliterature.However,eachalgorithmhasitsbias,beingmoreade-
quate forparticulardatasets.Thispaperpresentsamathematicalformulationtosupportthecreationof
consistent clustersforbiologicaldata.Moreover,itshowsaclusteringalgorithmtosolvethisformulation
that usesGRASP(GreedyRandomizedAdaptiveSearchProcedure).Wecomparedtheproposedalgorithm
with threeknownotheralgorithms.Theproposedalgorithmpresentedthebestclusteringresultscon-
firmed statistically.
Keywords :
Clustering , GRASP , Gene expression data , Bioinformatics
Journal title :
Computers and Operations Research
Journal title :
Computers and Operations Research