Author/Authors :
Beigh ، A. B. نويسنده Department of Veterinary Pathology, College of Veterinary Sciences, Guru Angad Dev Veterinary and Animal Sciences University, Ludhiana-141004, India. , , Sandhu ، B. S. نويسنده Department of Veterinary Pathology, College of Veterinary Sciences, Guru Angad Dev Veterinary and Animal Sciences University, Ludhiana-141004, India. , , Singh ، C. K. نويسنده Department of Veterinary Pathology, College of Veterinary Sciences, Guru Angad Dev Veterinary and Animal Sciences University, Ludhiana-141004, India. , , Bansal ، K. نويسنده Veterinary Officer, Veterinary Polytechnic and Regional Research Training Centre, Guru Angad Dev Veterinary and Animal Sciences University, India. , , Sood ، N. K. نويسنده Department of Veterinary Pathology, College of Veterinary Sciences, Guru Angad Dev Veterinary and Animal Sciences University, Ludhiana-141004, India. ,
Abstract :
In the present study, histomorphological alterations in nervous tissue of 15 cows were envisaged for diagnosis of rabies virus lesions. Sensitivity of histomorphological alterations was compared with Fluorescence Antibody Technique (FAT). On the basis of Negri body detection and histomorphological alterations, rabies were confirmed in 7 (46.6%) cases while, FAT detected rabies viral antigen in 9 (60%) cases. Sensitivity of histomorphological study as compared with FAT was found to be 88.18%. Quantitative assessments of other histomorphological alterations reported were Gliosis, Neuronal degeneration, Congestion, Perivascular cuffing, Satellitosis, Hemorrhages, Edema, Meningitis, Neuronophagia, Babes’ nodules, Spongiosis and Vacuolation in Negri bodies. It was concluded that detection of Negri bodies was quite consistent in cows with the presence of pathognomonic lesions of rabies viz. Negri bodies in 100% cases in the present study.
