Title of article :
Antidiarrhoeal Activity of Ethanolic Extract of Adansonia digitata Fruit Pulp in Rats
Author/Authors :
Maha ، Y. نويسنده Department of Pharmacology and Toxicology Faculty of Veterinary Medicine University of Khartoum- Sudan. , , Abdelrahim، - نويسنده Department of Pharmacology and Toxicology Faculty of Veterinary Medicine University of Khartoum- Sudan. , , Babiker ، M. A. نويسنده Department of Pharmacology and Toxicology Faculty of Veterinary Medicine University of Khartoum- Sudan. , , Elamin ، D. J. نويسنده Department of Medicine Pharmacology and Toxicology collage of Veterinary Medicine University of Bahri. , , Khalil، - نويسنده Department of Pharmacology and Toxicology Faculty of Veterinary Medicine University of Khartoum- Sudan. , , Samia ، M. A. E. نويسنده Department of Pharmacology and Toxicology Faculty of Veterinary Medicine University of Khartoum- Sudan. , , Badwi، - نويسنده Department of Pharmacology and Toxicology Faculty of Veterinary Medicine University of Khartoum- Sudan. ,
Issue Information :
روزنامه با شماره پیاپی 0 سال 2013
Abstract :
The antidiarrhoeal activity of ethanolic extract of Adansonia digitata fruit pulp was evaluated in rats. Studies were investigated on castor oil –induced diarrhoea, castor oil induced fluid accumulation and electrolyte secretion. Adansonia digitata was orally administered to rats at dose rate of 250 and 500mg/kg and Loperamide was used at 3mg/kg as reference antidiarrhoeal drug.The extract produced a dose dependant and significantly protected rats against castor oil induced diarrhoea. The frequency of defecation as well as weight of the feces was significantly (p > 0.05) reduced.A preliminary phytochemical screening of the ethanolic extract of A. digitata revealed the presence of, flavonoids, saponins, tannins triterpenes, alkaloids and glycosides.
Journal title :
Journal of Physiology and Pharmacology Advances
Journal title :
Journal of Physiology and Pharmacology Advances
