• Title of article

    Thin Layer Chromatographic Analysis of Beta-Lactam Antibiotics

  • Author/Authors

    Hancu، Gabriel نويسنده Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Medicine and Pharmacy, Târgu Mure?, Romania. , , Simon، Brigitta نويسنده Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Medicine and Pharmacy, Târgu Mure?, Romania. , , Kelemen، Hajnal نويسنده Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Medicine and Pharmacy, Târgu Mure?, Romania. , , Rusu، Aura نويسنده Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Medicine and Pharmacy, Târgu Mure?, Romania. , , Mircia، Eleonora نويسنده Department of Organic Chemistry, Faculty of Pharmacy, University of Medicine and Pharmacy, Târgu Mure?, Romania. , , Gyéresi، ?rp?d نويسنده Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Medicine and Pharmacy, Târgu Mure?, Romania. ,

  • Issue Information
    دوفصلنامه با شماره پیاپی 0 سال 2013
  • Pages
    5
  • From page
    367
  • To page
    371
  • Abstract
    Purpose: The paper describes some thin layer chromatographic procedures that allow simple and rapid separation and identification of penicillins and cephalosporins from complex mixtures. Methods: Using silicagel GF254 as stationary phase and selecting different mobile phases we succeeded in the separation of the studied beta-lactamins. Our aim was not only to develop a simple, rapid and efficient method for their separation but also the optimization of the analytical conditions. Results: No system will separate all the beta-lactams, but they could be identified when supplementary information is used from color reactions and/or by using additional chromatographic systems. Conclusions: The right combination of solvent system and detection method allows the identification of the studied penicillins and cephalosporins and can be successfully used in the preliminary analysis beta-lactam antibiotics.
  • Journal title
    Advanced Pharmaceutical Bulletin
  • Serial Year
    2013
  • Journal title
    Advanced Pharmaceutical Bulletin
  • Record number

    945947