Author/Authors :
Khatami، Seyedeh Mahsa نويسنده . Department of Biology, Cell and Molecular Laboratory, Faculty of Science, University of Mohaghegh Ardabili, Ardabil, Iran , , Zahri، Saber نويسنده , , Maleki، Masoud نويسنده , , Hamidi، Kamaloddin نويسنده Department of Biology, Cell and Molecular Laboratory, Faculty of Science, University of Mohaghegh Ardabili, Ardabil, Iran ,
Abstract :
Recently, the use of stem cells has expanded into numerous areas including cell therapy. In
this study, we investigated the differentiation capacity of human Wharton’s jelly stem cells
(hWJSCs) into lens fiber cells. Morphological changes and expressions of four crystallin
genes (?A, ?B, BB1 and BB3) were studied. The bovine vitreous body has been shown to
induce expression of crystallin genes in hWJSCs. By using the vitreous as a lens fiber cell
inducer, we showed that ?B-, BB1- and BB3-crystallin genes expressed in hWJSCs.
