Author/Authors :
Mohammad-Taheri، Zohreh نويسنده , , Ryahi، Mohammad Mehdi نويسنده Virology Research Center, NRITLD, Shahid Beheshti University, M.C., TEHRAN-IRAN , , Nadji، Seyed Alireza نويسنده Virology Research Center, NRITLD, Masih Daneshvari Hospital, Shahid Beheshti University of Medical Sciences, TEHRAN-IRAN. , , Mohammadi، Forouzan نويسنده ,
Abstract :
Epstein-Barr virus (EBV) is one of the most important causes of hemophagocytic syndrome. We report a 76-year-old man
who presented with pneumonia like symptoms and pleural effusion following upper respiratory tract infection. He underwent
thoracentesis and pleural fluid cytology revealed large number of histiocytic macrophages that had phagocytosed RBCs and
other inflammatory cells like lymphocytes and neutrophils.
Pleural fluid analysis showed Epstein-Barr virus Antigen (EBNA) as the causing agent and corticosteroid therapy was
initiated. A few days later, pleural effusion subsided and further cytologic examinations revealed no trace of
hemophagocytosis.
