Author/Authors :
Akiyoshi Sawabe، نويسنده , , Masanori Morita، نويسنده , , Tatsuya Kiso، نويسنده , , Hideki Kishine، نويسنده , , Yoshikazu Ohtsubo، نويسنده , , Toshie Minematsu، نويسنده , , Yoshiharu Matsubara، نويسنده , , Tadashi Okamoto، نويسنده ,
Abstract :
Three limonoid glycosides were isolated from Citrus unshiu peels, and their structures were determined based on MS and NMR spectroscopic data as nomilinic acid 17-O-β-d-glucopyranoside (1), methyl nomilinate 17-O-β-d-glucopyranoside (2), and obacunone 17-O-β-d-glucopyranoside (3). In particular, the location of the sugar moiety was clearly determined by the B/E constant linked scan FABMS method. No limonoid glycosides obtained here were found to have antitumor activity in NCI-H292 and EL-4 cell lines.
Keywords :
Citrus unshiu , Methyl nomilinate 17-O-?-d-glucopyranoside , B/E constant linked scan FABMS , Limonoid glycosides
