Stereospecific α-d-mannosylation

The stereospecific formation of α-d-mannosyl glycosidic linkages has been achieved in high yield using tetra-O-pivaloyl-α-d-mannopyranosyl fluoride and boron trifluoride diethyl etherate in dichloromethane. Examples of the α-d-mannosylation of primary, secondary, benzylic and phenolic hydroxyl groups are described.