1,5-Anhydro-d-fructose: regioselective acylation with fatty acids

Regioselective acylation of 1,5-anhydro-d-fructose was performed with dodecanoic acid to give 1,5-anhydro-6-O-dodecanoyl-d-fructose, chemically in 50% yield and enzymatically in quantitative yield. Quantitative conversions were also obtained using hexadecanoic and octadecanoic acids as acyl donors.