Title of article
Enzymatic glycosylation using 6-O-acylated sugar donors and acceptors: β-N-acetylhexosaminidase-catalysed synthesis of 6-O,N,N′-triacetylchitobiose and 6′-O,N,N′-triacetylchitobiose Original Research Article
Author/Authors
Lucie Hu??kov?، نويسنده , , Sergio Riva، نويسنده , , Monica Casali، نويسنده , , Silvia Nicotra، نويسنده , , Marek Kuzma، نويسنده , , Zdenka Hu?kov?، نويسنده , , Vladim??r K?en، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2001
Pages
6
From page
143
To page
148
Abstract
p-Nitrophenyl 6-O-acetyl-2-acetamido-2-deoxy-β-d-glucopyranoside (5a) was used as the glycosyl donor in a β-N-acetylhexosaminidase-catalysed (from Penicillium brasilianum) glycosylation of GlcNAc yielding 6′-O,N,N′-triacetylchitobiose (6), while 6-O-acetyl-2-acetamido-2-deoxy-β-d-glucopyranose (3a) served as a selectively protected acceptor in a transglycosylation reaction catalysed by the same enzyme to yield 6-O,N,N′-triacetylchitobiose (4).
Keywords
Chitobiose , Acylated glycosyl donor , Enzymatic acylation , ?-N-Acetylhexosaminidase
Journal title
Carbohydrate Research
Serial Year
2001
Journal title
Carbohydrate Research
Record number
963150
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