Efficient intramolecular β-mannoside formation using m-xylylene and isophthaloyl derivatives as rigid spacers Original Research Article

A series of mannosyl donors linked via position 2 to an m-xylylene or an isophthaloyl spacer which was connected to the position 6 of a glucoside acceptor afforded, via intramolecular glycosylation, the corresponding disaccharides with high β anomeric ratio.