Synthesis of dimeric lactose and dimeric (sialyl) LewisX glycolipids Original Research Article

To investigate structural requirements for the homophilic interaction between carbohydrates on planar model membranes, divalent derivatives with enforced proximity between the two carbohydrate epitopes (lactose, LewisX, and sialyl LewisX) were synthesized by use of a dimeric membrane anchor as scaffold.