Title of article :
Synthesis of ceramidated GLA-60 derivatives Original Research Article
Author/Authors :
Tsuyoshi Nakamura، نويسنده , , Masao Shiozaki، نويسنده , , Shinichi Kurakata، نويسنده ,
Issue Information :
دوهفته نامه با شماره پیاپی سال 2002
Abstract :
Ceramidated GLA-60 derivatives 11 and 11′ were synthesized from 1 via glycosidation of ceramide derivative 12 as a glycosyl acceptor with GLA-60 derivative 5 as a glycosyl donor, and successive conversion. Compound 11′ showed only weak LPS-antagonistic activity without showing any LPS-agonistic activity.
Keywords :
Glycosidation , Glycosphingolipids , LPS-antagonist , Ceramidated GLA-60 derivatives
Journal title :
Carbohydrate Research
Journal title :
Carbohydrate Research
