Author/Authors :
Qing Li، نويسنده , , Bin Su، نويسنده , , Hui Li، نويسنده , , Xiang-Bao Meng، نويسنده , , Meng-Shen Cai، نويسنده , , Zhong-Jun Li، نويسنده , , Rou-Li Zhou، نويسنده , , Ta-Lin Suo، نويسنده ,
Abstract :
Anomers of monovalent and divalent β-d-galactopyranosyl-(1→4)-2-acetamido-2-deoxy-d-gluco-pyranosides were synthesized under different glycosylation conditions, and evaluated for in vitro antimetastatic activity. Three compounds showed promising inhibitory effects on cancer cell attachment, spreading, migration, and invasion.
Keywords :
Monovalent , N-Acetyllactosamine , Divalent , Metastasis , Synthesis