Title of article :
First round of a focused library of cholera toxin inhibitors Original Research Article
Author/Authors :
Crtomir Podlipnik، نويسنده , , Ingrid Velter، نويسنده , , Barbara La Ferla، نويسنده , , Gilles Marcou، نويسنده , , Laura Belvisi، نويسنده , , Francesco Nicotra، نويسنده , , Anna Bernardi، نويسنده ,
Issue Information :
دوهفته نامه با شماره پیاپی سال 2007
Pages :
10
From page :
1651
To page :
1660
Abstract :
C-Galactosides have been used as scaffolds to design a library of non-hydrolysable inhibitors of cholera toxin (CT). Test elements from the library were synthesized and found to inhibit CT binding to an asialofetuin-coated SPR chip with micromolar affinity. Preliminary results are reported.
Keywords :
cholera toxin , Glycomimetics , Carbohydrate mimics , GM1 ganglioside , C-Glycosides
Journal title :
Carbohydrate Research
Serial Year :
2007
Journal title :
Carbohydrate Research
Record number :
964778
Link To Document :
https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=964778
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