Author/Authors :
Kuo-Ting Huang، نويسنده , , Bing-Ching Wu، نويسنده , , Chang-Ching Lin، نويسنده , , Shih-Chi Luo، نويسنده , , Chinpan Chen، نويسنده , , Chi-Huey Wong، نويسنده , , Chun-Cheng Lin، نويسنده ,
Abstract :
An enzymatic one-pot three-step glycosylation strategy was developed for the synthesis of sLex moiety of truncated PSGL-1 glycopeptide with and without sulfation. The method provided an efficient way to afford complex glycopeptides in a semi-preparative scale without further complicated and time-consuming purification process in each glycosylation step.
Keywords :
Glycosyltransferase , One-pot synthesis , Sialyl Lewis X , PSGL-1 , Glycopeptide
