Author/Authors :
Gracia Mendoza، نويسنده , , Ana I. ?lvarez، نويسنده , , Mivis M. Pulido، نويسنده , , Antonio J. Molina، نويسنده , , Gracia Merino، نويسنده , , Rebeca Real، نويسنده , , Peter Fernandes، نويسنده , , Julio G. Prieto، نويسنده ,
Abstract :
Hyaluronan (HA) was depolymerized by hydroxyl radicals generated from hydrogen peroxide and cupric ions. Inhibition of HA degradation by four well-known antioxidants was investigated, as HA can scavenge reactive oxygen species (ROS). Change in hyaluronan molecular weight was observed by size-exclusion chromatography. Inhibition of HA degradation was estimated from the retention times observed.
Keywords :
Mannitol , Propofol , Thiourea , Reactive oxygen species , Vinpocetine , antioxidant , Hyaluronan
