Title of article
Study on glycosylated prodrugs of toxoflavins for antibody-directed enzyme tumor therapy
Author/Authors
Shusheng Wang، نويسنده , , Dan Liu، نويسنده , , Xu Zhang، نويسنده , , Shengyu Li، نويسنده , , Yongxu Sun، نويسنده , , Jia Li، نويسنده , , Yifa Zhou، نويسنده , , Liping Zhang، نويسنده ,
Issue Information
دوهفته نامه با شماره پیاپی سال 2007
Pages
7
From page
1254
To page
1260
Abstract
Eight novel toxoflavin glycosides, which are potential prodrugs in antibody directed enzyme prodrug therapy (ADEPT), were synthesized. The structures of all toxoflavin glycosides were characterized by 13C NMR spectroscopy, elemental analysis, and MS. Their enzymatic hydrolysis activities were tested against β-glucosidase (EC.3.2.1.21).
Keywords
Toxoflavins , Toxoflavin glycosides , Prodrugs , ?-Glucosidase , Anticancer
Journal title
Carbohydrate Research
Serial Year
2007
Journal title
Carbohydrate Research
Record number
965211
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