Title of article
Preparation of 6,6,1′,1′,6′,6′-hexadeutero sucrose
Author/Authors
Marie-Hélène Gouy، نويسنده , , Mathieu Danel، نويسنده , , Maud Gayral، نويسنده , , Alain Bouchu، نويسنده , , Yves Queneau، نويسنده ,
Issue Information
دوهفته نامه با شماره پیاپی سال 2007
Pages
6
From page
2303
To page
2308
Abstract
The preparation of 6,6,1′,1′,6′,6′-hexadeutero sucrose is reported. The synthesis is based on a triple oxidation of a protected sucrose 6,1′,6′-triol to the corresponding 6,1′,6′-tricarboxylic acid or ester, followed by reduction with lithium aluminium deuteride. This triple oxidation could be achieved either using cat. TEMPO–NaOCl (to the acid) or PDC–Ac2O–t-BuOH (to the t-butyl carboxylic ester).
Keywords
Deuteration , Sucrose , Uronic acids , Oxidation , Labelled compounds , TEMPO , Isotope
Journal title
Carbohydrate Research
Serial Year
2007
Journal title
Carbohydrate Research
Record number
965329
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