Title of article
Synthesis of novel ribavirin hydrazone derivatives and anti-proliferative activity against A549 lung cancer cells Original Research Article
Author/Authors
Wei-Yong Liu، نويسنده , , Haiying Li، نويسنده , , BaoXiang Zhao، نويسنده , , Dongsoo Shin، نويسنده , , Song Lian، نويسنده , , JunYing Miao، نويسنده ,
Issue Information
دوهفته نامه با شماره پیاپی سال 2009
Pages
6
From page
1270
To page
1275
Abstract
A series of novel ribavirin hydrazone derivatives were synthesized by the reaction of ribavirin hydrazone with benzaldehyde or acetophenone derivatives. The structures of the compounds were determined by IR, 1H NMR, and HRESIMS. Preliminary biological evaluation showed that one compound (7h) inhibits the growth of A549 cells at 20 μM.
Keywords
A549 cells , Ribavirin hydrazone , Synthesis , Biological evaluation
Journal title
Carbohydrate Research
Serial Year
2009
Journal title
Carbohydrate Research
Record number
966448
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