Title of article
Synthesis of Lewis X epitopes on plant N-glycans Original Research Article
Author/Authors
Gerard J.A. Rouwendal، نويسنده , , Dion E.A. Florack، نويسنده , , Thamara Hesselink، نويسنده , , Jan H. Cordewener، نويسنده , , Johannes P.F.G. Helsper، نويسنده , , Dirk Bosch، نويسنده ,
Issue Information
دوهفته نامه با شماره پیاپی سال 2009
Pages
7
From page
1487
To page
1493
Abstract
Glycoproteins from tobacco line xFxG1, in which expression of a hybrid β-(1→4)-galactosyltransferase (GalT) and a hybrid α-(1→3)-fucosyltransferase IXa (FUT9a) is combined, contained an abundance of hybrid N-glycans with Lewis X (LeX) epitopes. A comparison with N-glycan profiles from plants expressing only the hybrid β-(1→4)-galactosyltransferase suggested that the fucosylation of the LacNAc residues in line xFxG1 protected galactosylated N-glycans from endogenous plant β-galactosidase activity.
Keywords
Tobacco , Transgenic , ?-(1?4)-galactosyltransferase , ?-(1?3)-Fucosyltransferase , N-Glycan , Lewis x
Journal title
Carbohydrate Research
Serial Year
2009
Journal title
Carbohydrate Research
Record number
966477
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