• Title of article

    Synthesis of a trigalacturonic acid analogue mimicking the expected transition state in the glycosidases Original Research Article

  • Author/Authors

    Kazunori Yamamoto، نويسنده , , Shogo Noguchi، نويسنده , , Noboru Takada، نويسنده , , Kazuo Miyairi، نويسنده , , Masaru Hashimoto، نويسنده ,

  • Issue Information
    دوهفته نامه با شماره پیاپی سال 2010
  • Pages
    14
  • From page
    572
  • To page
    585
  • Abstract
    A trigalacturonic acid analogue carrying a cyclohexene framework in place of the central pyranose ring was synthesized as a molecular probe for the mechanistic investigation of endo-polygalacturonase 1 (endo-PG 1). Preliminary enzymatic studies revealed that this analogue inhibited endo-PG 1 activity by about 30% at 0.3 mM concentration.
  • Keywords
    endo-Polygalacturonase 1 , Trigalacturonic acid analogue , Cyclohexene ring , Transition state structure
  • Journal title
    Carbohydrate Research
  • Serial Year
    2010
  • Journal title
    Carbohydrate Research
  • Record number

    966714

    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=966714