Title of article :
Indium-mediated alkynylation of sugars: synthesis of C-glycosyl compounds bearing a protected amino alcohol moiety
Author/Authors :
Charfedinne Ayed، نويسنده , , Sara Palmier، نويسنده , , Nadège Lubin-Germain، نويسنده , , Jacques Uziel، نويسنده , , Jacques Augé، نويسنده ,
Issue Information :
دوهفته نامه با شماره پیاپی سال 2010
Abstract :
The coupling of glycals with an alkynyl iodide bearing a protected amino alcohol moiety was achieved in the presence of metallic indium under Barbier conditions. It gave functionalized C-glycosyl compounds, precursors of C-glycosyl amino acids with α configuration.
Keywords :
C-Glycosylation , Glycopeptides , Anomeric reactivity , Organometallic coupling , Indium , Alkynylation
Journal title :
Carbohydrate Research
Journal title :
Carbohydrate Research