Title of article
Rapid glycosylations under extremely mild acidic conditions. Use of ammonium salts to activate glycosyl phosphites via P-protonation
Author/Authors
Fumiko Matsumura، نويسنده , , Shiro Tatsumi، نويسنده , , Natsuhisa Oka، نويسنده , , Takeshi Wada، نويسنده ,
Issue Information
دوهفته نامه با شماره پیاپی سال 2010
Pages
5
From page
1211
To page
1215
Abstract
Trifluoromethanesulfonic acid salts of tertiary amines were employed as extremely mild acidic activators for rapid glycosylations. Glycosyl phosphite triesters bearing an acid-labile 4,4′-dimethoxytrityl (DMTr) group for transient protection worked as glycosyl donors effectively in the presence of the activators to afford the corresponding disaccharides in good yields without loss of the DMTr group.
Keywords
Glycosylation , Glycosyl phosphites , Ammonium salts , 4 , P-Protonation , 4?-Dimethoxytrityl group
Journal title
Carbohydrate Research
Serial Year
2010
Journal title
Carbohydrate Research
Record number
967000
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