Title of article
Investigation of glycosylating properties of 1-deoxy-1-ethoxysulfonyl-hept-2-ulopyranosyl derivatives. Synthesis of a new sulfonic acid mimetic of the sialyl Lewis X tetrasaccharide Original Research Article
Author/Authors
Magdolna Cs?v?s، نويسنده , , G?bor M?jer، نويسنده , , Mih?ly Herczeg، نويسنده , , Judit Remenyik، نويسنده , , L?szl? L?z?r، نويسنده , , Attila M?ndi، نويسنده , , Anik? Borb?s، نويسنده , , S?ndor Antus، نويسنده ,
Issue Information
دوهفته نامه با شماره پیاپی سال 2011
Pages
7
From page
1527
To page
1533
Abstract
Glycosylation reactions of the ethylthio, bromo and chloro derivatives of 1-deoxy-1-ethoxysulfonyl-hept-2-ulopyranose were studied applying different acceptors under different conditions. Elimination side-reactions affording exo- and endoglycals occured in all cases, however, with different proportions. Glycosyl chloride donor was applied to glycosylate a trisaccharide acceptor obtaining a new sulfonic acid mimetic of the sialyl Lewis X tetrasaccharide in high yield.
Keywords
Glycosylation , Elimination , Ketopyranosyl glycosides , Carbohydrate sulfonic acid , Sialyl Lewis X mimetic
Journal title
Carbohydrate Research
Serial Year
2011
Journal title
Carbohydrate Research
Record number
967214
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