Title of article
Synthetic and semi-synthetic chondroitin sulfate oligosaccharides, polysaccharides, and glycomimetics Original Research Article
Author/Authors
Emiliano Bedini، نويسنده , , Michelangelo Parrilli، نويسنده ,
Issue Information
دوهفته نامه با شماره پیاپی سال 2012
Pages
11
From page
75
To page
85
Abstract
Chondroitin sulfate (CS) is a sulfated polysaccharide involved in a myriad of biological processes. Due to the variable sulfation pattern of CS polymer chains, the need to study in detail structure–activity relationships regarding CS biomedical features has provoked much interest in obtaining synthetic CS species. This paper reviews two decades of synthetic and semi-synthetic CS oligosaccharides, polysaccharides, and glycomimetics obtained by chemical, chemoenzymatic, enzymatic, and microbiological-chemical strategies.
Keywords
Semi-synthesis , Chondroitin sulfate , Glycosaminoglycan , Total synthesis
Journal title
Carbohydrate Research
Serial Year
2012
Journal title
Carbohydrate Research
Record number
967592
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