Title of article
A convenient synthesis of N-linked diglycose derivatives based on one-pot tandem Staudinger/aza-Wittig/reduction and biological evaluation Original Research Article
Author/Authors
Pingzhu Zhang، نويسنده , , Yinbo Li، نويسنده , , Ming Liu، نويسنده , , Yanfei Wang، نويسنده , , Cuicui Li، نويسنده , , Donglai Ma، نويسنده , , Hua Chen، نويسنده , , Kerang Wang، نويسنده , , Xiaoliu Li، نويسنده , , Jinchao Zhang، نويسنده ,
Issue Information
دوهفته نامه با شماره پیاپی سال 2013
Pages
8
From page
15
To page
22
Abstract
A series of novel N-linked diglycose derivatives 9 and 10 were conveniently and directly synthesized based on the key step of one-pot tandem Staudinger/aza-Wittig/reduction reaction from the azido sugar and sugar-derived aldehyde followed by deprotection. The biological activities against glycosidases (α-amylase, α-glucosidase, and β-glucosidase) and HIV-RT and antitumor activity of these compounds were preliminarily evaluated.
Keywords
Staudinger/aza-Wittig/reduction , N-linked diglycoses , Glycosidase inhibition , Antitumor , One pot reaction
Journal title
Carbohydrate Research
Serial Year
2013
Journal title
Carbohydrate Research
Record number
967866
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