Tetracycline residues in bones of slaughtered animals

The incidence of tetracycline (TC) residues in bones of slaughtered animals (pigs, turkeys, chickens, ducks and calves) was investigated using a screening fluorescence test and HPLC analysis. Fluorescence findings vary from 18.8% to 100% depending on species. The concentrations of TCs in the bones were 0.14–50.0 mg kg−1. Additionally, an experimental evaluation of the specifity and sensitivity of the fluorescence screening test was performed. Chickens were fed low dosages of oxytetracycline (OTC) and subsequently analysed for detectable residues after a withdrawal period of 1, 5, 15 and 25 days. The results are discussed with regard to the possible toxicological significance of TC residues in bones