Title of article
Development and validation of a method for the determination of sulfonamides in animal feed by modified QuEChERS and LC–MS/MS analysis
Author/Authors
Renata Pereira Lopes، نويسنده , , Erica Eust?quia de Freitas Passos، نويسنده , , Juarez Fabiano de Alkimim Filho، نويسنده , , Eugênia Azevedo Vargas، نويسنده , , Daniella Vasconcellos Augusti، نويسنده , , Rodinei Augusti، نويسنده ,
Issue Information
ماهنامه با شماره پیاپی سال 2012
Pages
7
From page
192
To page
198
Abstract
A multiresidue method for the quantification of 13 sulfonamides in animal feed is described. It involves the application of a modified QuEChERS procedure followed by HPLC–MS/MS (high performance liquid chromatography coupled to tandem mass spectrometry) analysis. The best conditions for the extraction solution and PSA (primary secondary amine) mass were determined. After optimization, the method was validated according to the European Commission Decision 2002/657/EC. The validation levels employed were 25, 50 and 75 μg kg−1. Acceptable values were obtained for the following parameters: linearity (0.9864 < r2 < 0.9993), decision limit (50.4 μg kg−1 < CCα < 55.8 μg kg−1), detection capability (50.7 μg kg−1
Keywords
Animal feed , QuEChERS , HPLC–MS/MS , Sulfonamides
Journal title
Food Control
Serial Year
2012
Journal title
Food Control
Record number
977438
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