Author/Authors :
Mats Allmyra، نويسنده , , b، نويسنده , , ?، نويسنده , , Fiona Hardenc، نويسنده , , d، نويسنده , , Leisa-Maree L. Tomsc، نويسنده , , Jochen F. Muellerc، نويسنده , ,
Michael S. McLachlanb، نويسنده , , Margaretha Adolfsson-Ericib، نويسنده , , Gunilla Sandborgh-Englunda، نويسنده ,
Abstract :
The bactericide triclosan has found wide-spread use in e.g. soaps, deodorants and
toothpastes. Recent in vitro and in vivo studies indicate that triclosan might exert adverse
effects in humans. Triclosan has previously been shown to be present in human plasma and
milk at concentrations that are well correlated to the use of personal care products
containing triclosan. In this study we investigated the influence of age, gender, and the
region of residence on triclosan concentrations in pooled samples of Australian human
blood serum. The results showed no influence of region of residence on the concentrations
of triclosan. There was a small but significant influence of age and gender on the serum
triclosan concentrations, which were higher in males than in females, and highest in the
group of 31–45 year old males and females. However, overall there was a lack of pronounced
differences in the triclosan concentrations within the dataset, which suggests that the
exposure to triclosan among different groups of the Australian population is relatively
homogenous. A selection of the dataset was compared with previous measurements of
triclosan concentrations in human plasma from Sweden, where the use of triclosan is
expected to be low due to consumer advisories. The triclosan concentrations were a factor of
2 higher in Australian serum than in Swedish plasma.
