شماره ركورد :
17198
عنوان به زبان ديگر :
Vasorelaxatory Effect of Vitis vinifera Extract on Rat Aorta
پديد آورندگان :
Gharib Naseri Mohammad Kazem نويسنده , Navid Hamidi Mojdeh نويسنده , Heidari Akbar نويسنده
از صفحه :
93
تا صفحه :
99
تعداد صفحه :
7
چكيده لاتين :
Reports have shown the antioxidant, hypotensive, hypolipidemic and vasodilatory effects
of grape (Vilis vinifera L.) seed extract. We have recently shown the relaxatory effec t of
grap e leaf extract on rat uterus and redu ction of frog heart rate and con tractility. The aim of
the present study was to inve stigate the relaxant effect of Vilis vinifera leaf hydroalcoholic
extract (VLHE) on rat thora cic aorta contractions induced by phenylephrine and KCI and the
role of aorta endothelium on this action. Rat aort a was remo ved and placed in an organ bath
containing Krebs-Henseleit solution and aorta contractions were recorded isometrica lly.
The results demonstrate that VLHE (0.125-2 mg/ml) redu ces the end othelial intact aorta
recon stru cted by phen ylephrine ( I ~IM) dose-dependently (P
شماره مدرك :
1201120
لينک به اين مدرک :
