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INTRATHECAL MIDAZOLAM P THE ANALGESIC EFFECTS OF SPINAL BLOCKADE WITH LIDOCAINE FOR PERINEAL OPERATION

354

356

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Intra theca l administration of midazolam has been reported to have anti n ciccptive action, and to be an effective analgesic agent. In this pros pective double-blind study we aimed to eva lua te the postoperative effects of intrathecal midazoIam with lidocaine following perineal operation. Forty patients were randomly allocated to two groups: 20 patients in the control group received 2 ml of 5% heavy lidocaine plus 0.4 ml of 0.9% saline intrathecally; 20 patients in the midazolam group received 2 ml of 5% heavy lidoca ine plus 0.4 ml of 0.5% midazolam. Duration of ana lgesia was sign ificantly greater in the midazolam group (7 ± I hours) compared to the control group ( 1.5 ± 0.5 hours) . Acta Medica Iran ica, 44(5) : 354-354; 2006 .© 2006 Tehran University of Medical Sciences. All rights reserved.

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