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Fowl cholera: Evaluation of a Trivalent Pasteurella multocida Vaccine Consisted of Serotypes 1,3 and 4

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An inactivated trivalent fowl cholera vaccine consisted of serotypes 1, 3 and 4 Pasteurella multocida strains was prepared. The vaccine provided 70-100% protection against challenge with homologous starins. ELISA assay showed a considerable increase in antibody titer after towice vaccination of 8 weeks chickens. It was found that the trivalent vaccine can induce immunogenic response in vaccinated chickens.

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