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One-Pot Facile Conversion of Baylis-Hillman Adducts into 1,5-Diarylpyrazoles Using Microwave Irradiation

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Several Baylis-Hillman adducts were prepared by the reaction of appropriate arylaldehydes with methyl vinyl ketone in the presence of imidazole and a catalytic amount of L-proline, in 55-90% yields. An easy transformation of these adducts into 1,5- diarylpyrazoles was achieved using microwave irradiation (400 W) with short reaction times (1-3 min) and high yields (80-91%).

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