چكيده لاتين :
Background: Traditi onally some people employ Ocimum
basilicuni (Shas pram) to re lieve the symptoms of dy sp epsia.
We therefore stud ied the effects of oral extract of thi s medicinal
plant o n functi onal dy sp ep sia .
Methods: In a double-blind placebo-controll ed c linica l trial ,
th e effect of a four-week tre atment of Sh aspram was eva luated
0 11 fun ctional dysp ep sia. Two hundred cases from a ll pati ent s
referred for dysp epsia without hav ing any o bv ious pathologic
s igns were randoml y divid ed into case and co ntro l groups (100
eac h) . The hydroalcoholic ex trac t of leaves of Shaspram was
prepared and used . Pat ient s were asked to hav e 30 drop s of prescribed
medi cations (placebo or the ex tract, equa l to 1.5 gram
leaves powd er) dail y at 30 min befor e lunch and dinner for
four-weeks. Severity was scored for eac h symptom on a numbered
sca le and the res ults compared with th e results of placebo
group or pretr eatment period .
Results: Pati ents in dru g gro up resp onded to treatment bett er
than pati ent s in placebo gro up ( P(LESS THAN)O.OOI). Shasprarn was more
effec tive in fem ale and yo ung patients. Pati ents with fun ction al
dyspepsia that had dysmotility problems a lso responded to
Shas pram better than others.
Conclusion: Ocim um basilicum see ms to reI ieve th e sympto ms
of fun cti on al dysp epsia es pec ia lly in fema le and young patients
with dysm oti lity.
