مرکز منطقه ای اطلاع رساني علوم و فناوري -

چكيده لاتين :

Background: The aim of this study was to investigate the effec t of body mass index (BMI) on the outcome of in vitro fertilization (IVF)I intracytoplasmic sperm injection (ICS!) cyc les in non polyc ysti c ov ary syndrome (PCOs) women. Materials and Methods: In this cross sectional study, 287 infertile non PCOs women referred to Royan institute, Tehran, Iran between 2002 and 2003 were enrolled. Patient s with age24 0 years old or BMI <20 Kg/mי were excluded. All of patients underwent IVF or ICSI cycles. The outcome of ass isted rep roductive technology (ART) were compared between three groups: patients with 20S BMIS25 (nonnaI weight gro up); patients with 25< BMIS30 (over weight) and patients with 8Ml more than 30 Kg/rn? (obese group). ANOVA, T test, Chi-square and logistic regression were used for analysis.P value less than 0.05 was considered as significant level. Results: One hundred thirty three (46.3%) subje cts had normal BMI, 117 women (40.8%) were overwe ight and 37 women ( 12.9%) were obese. Obese group had lower pregnancy rate ( 13.5%) in comparision to normal (29.3%) and overweight (21.4%) groups although this difference was not statistically signifi cant (p=0.09). Chi square analysis showed that normal weight women had significantly higher regular mensturation (p=O.02). The logestic regression analysis showed that BMI significantly affects on pregnancy rate ofART cyc les in non PCOs women (p=O.038) . Conclusion: The finding of this study suggested that in non PCOs wome n, 8MI had independent adverse effect on the pregnancy rate of IVF/ICSI cycles.