SOME IMMUNOSUPPRESSIVE EFFECT OF T-2 TOXIN IN BROILER CHICKS

Male broiler 1-day-old chicks were fed T-2 toxin at a rate of 8 mg/kg for 3 weeks, to determine its effect on total leukocyte count; differential and absolute leukocyte count; stress ratio (Heterophils / Lymphocytes ), (H/L); serum albumin and globulin’s (α,β,δ )levels ; bursal weight index (BWI); bursal diameter index (BDI); Thymus length index (TDI); histological changes in both bursa of Fabricious and thymus. The results show that T-2 toxin had a significant negative effect on all of the above mentioned parameters, with cortical thinning effect on both bursa of Fabricious and thymus.