تحضير وتشخيص بعض المركبات الجديدة 2-مركبتو بنزاميدازول المشتقة من اورثو فنيلين ثنائي امين

Synthesis and characterization of some new2- mercapto benzimidazole derivative from ortho phenylenediamine

This the research includes synthesis of some new derivatives of 2-mercapto benzimidazole (N1), the compound (N1), prepared by reaction of o-phenylene diamine with carbon disulfide in alcoholic potassium hydroxide. Then the compound (N1) was treated with hydrazine hydrate in ethanol to give 2-hydrazinobenzimidazole ( N2).A Number of hydrazones (N3- N10) were synthesized from the reaction of compound (N2) with various substituted benzaldehydes (aceto phenone) gave hydrazone compounds(N3-N10).Substituted compounds(N11-N12) , compound (N13) , compounds(N14-N16) ,compounds (N17-N18),Were synthesized from cyclization of hydrazones (N3- N10) using chloro acetic acid or tri chloro acetic acid or thio glycolic acid or chloro acetyl chloride respectively. The synthesized compounds were identified according to their physical properties, spectroscopic data (IR and1H- NMR) in addition to systematic identification of some active functional groups in these compounds.