The effect of digoxin on the enzymatic activity of glutamate oxaloacetate transaminase

The investigation of glutamate oxaloacetate transaminase (GOT) activity to search the effect of digoxin drug on the enzyme activity of GOT, which this work carried out on sera (22) sample healthy individual in vitro. The result demonstrate that increased activity and non significance variation (P 0.07), when comparison of enzymatic activity with drug with that of enzymatic activity without drug for the same each sample .The activation percentage equal to (251%). Also experimented the volume effect from stock (0.5mg/2ml ), which the volume was give maximum activation equal to (40 μℓ).