تقييم فعالية البربوفول الوريدي وسلامته في التركين العميق للاطفال في العيادة السنية

Background & Objective: Pediatric dentists usually face problem in managing uncooperative pediatric patients. The aim of this study were to evaluate the efficacy and safety of intravenous propofol as deep sedation for uncooperative children, the efficacy of sedation using porpofol with intravenous short acting group of drugs (midazolam, ketamine and glycopyrrolate) and the effect of sex, age and treatment time on recovery time that required to discharge the patient. Methods & Materials: Study was carried out in pediatric dental center at Faculty of Dentistry,California University,LA,USA. ,A total of 33 uncooperative children included (16male, 17 female) ,their age was between 2-14 years(the mean age 8 years) who referred to the center for treatment under sedation due to failure of other behavioral managements, Retrospective study, Patients classified to (I,II) According to ASA. All children were given intravenous propofol with group of drugs (midazolam, ketamine and glycopyrrolate). The efficacy of propofol with group of drugs was evaluated on the basis of monitoring vital signs. Data were analyzed using Student’s t-tests. Results: There were no significant statistical difference in vital signs. Recovery time was short (5-60 min) with minimal side effect. There were no significant statistical correlation between recovery time and surgical time, sedation time and vital signs. Sedation time was suitable to perform all dental procedure ( 1h15min to 4h10min). There were no correlation between the gender of the child and the surgical time, sedation time and recovery time. There were insignificant statistical correlation between the age of the child and surgical time, sedation time and recovery time. Conclusion: Propofol appears to be safe and effective sedative agents for outpatient with short recovery time, therefore, intravenous sedation still be successful and acceptable more than general anesthesia.