المقارنة بين فعالية الامينوغلوبولين الوريدي IVIG و البريدنزلون في معالجة فرفرية نقص الصفيحات الاساسية الحادة عند الاطفال

This study included 26 patients aged between 3 months – 12 years who were hospitalized in Pediatrics Department at AL-ASSAD University Hospital in Latakia in one year (2005-2006) with different clinical features. It proved that they had thrombocytopenia, using the diagnosis of idiopathic thrombocytopenic purpura by marrow aspiration. The patients were divided into two groups: Group (1): intravenous immunoglobulin; it included 9 patients. Group (2): prednisolon; it included 17 patients. Both methods of treatment were employed, and platelet counts of the patients were determined at diagnosis, and at 2,3,5,7,14,30,90, and180 days of treatment. The percentages of patients with platelet counts above 20,000/ml on the 2nd day of the treatment were 88.8% (8 patients) in the first group, and 23.5% (5 patients) in the second group. The mean time for achievement of platelet counts above 100,000/ml was (4.2) days for the first group, and (21) days for the second one. There were significant differences in response to treatment in favor of immunoglobulin with a higher recovery percentage than prednisolon.