تكاثف بعض أمينو الآزولات مع الجليوكسال

Aminoazoles (1,3) react with aquous glyoxal to give a variety of compounds through different ways. The reaction mechanisms depend on reacted azole and solvent and (pH) reaction. 5- methyl-3- amino isoxazole was reacted with aquous glyoxal in i-propanol to give 1,2- N- bis 5- methyl-3- isoxazolyl diamino ethanediols but it gives 1,2- N- tetra 5- methyl -3 isoxazolyl tetra amino ethane in (Acetonitrile+Formic acid) at ambient temperature. On the other hand, 2-aminothiazole, 2-amino 4-methyl thiazole and 2-aminobenzothiazole were reacted with aquous glyoxal in (Acetonitril +formic acid) to yield 3,4,8,9- tetrahedroxy 7,10-di(2-thiazolyl) 2,5-dioxa-7,10- diaza bicycle[4,4,0] decane derivatives. In this report we present the results of this research which belong to a wide range of condensation of aminoazoles 1,3 with formaldehyde and glyoxal.