شماره ركورد كنفرانس :
1343
عنوان مقاله :
KF/HNTS CATALYZED ONE- POT THREE-COMPONENT BIGINELLI REACTIONS: AN EFFICIENT SYNTHESIS OF 3 , 4- DIHYDROPYRIMIDIN-2-(1H)-ONE
عنوان به زبان ديگر :
KF/HNTS CATALYZED ONE- POT THREE-COMPONENT BIGINELLI REACTIONS: AN EFFICIENT SYNTHESIS OF 3 , 4- DIHYDROPYRIMIDIN-2-(1H)-ONE
پديدآورندگان :
Ghanei Mercedeh نويسنده , Khalilzadeh Mohammad A. نويسنده , Mahmoodi Hashemi Mohammah نويسنده , Yavari Issa نويسنده
كليدواژه :
Biginelli reaction , multicomponent reaction , 3.4-dihydropyrimidin-2(1H)-ones , Solid base catalyst , KF/HNTs
عنوان كنفرانس :
چهارمين همايش ملي شيمي ، مهندسي شيمي و نانو ايران
چكيده لاتين :
Potassium fluoride/Holloysite nonotube (KF/HNTs) acts an active hetrogeneos base catalyst for Biginelli reaction. Here we have describe An efficient one-pot synthesis of 3,4- dihydropyrimidine-2(1H)-one via a three-component reaction of aldehyde, urea, and β-ketoester in the presence of a catalytic amount of (KF/HNTs). The experimental results showed that the KF/HNTs had high catalytic activity and it can be recycled without significant loss of activity. This protocols exhibit advantages such as excellent yield, easy work-up and eco-friendly conditions
شماره مدرك كنفرانس :
4456295