پديدآورندگان :
Masoum Saeed masoum@kashanu.ac.ir Department of Analytical Chemistry, Faculty of Chemistry, University of Kashan, Kashan, Iran , Samadi Naser Department of Chemistry, Faculty of Science, Urmia University, Urmia, Iran , Mehrara Bahare Department of Chemistry, Faculty of Science, Urmia University, Urmia, Iran , Mahboubi Mohadese Department of Microbiology, Research Center of Barij, Kashan, Iran
كليدواژه :
Chromatographic fingerprints , Satureja hortensis L. , Potentially antimicrobial compounds , Linear multivariate calibration , Independent component regression
چكيده فارسي :
Satureja hortensis L. is used in traditional medicine in the world due to its antifungal, antibacterial and antioxidant
properties. In this study, the antimicrobial activities in Satureja hortensis L. essential oils against three microbial
strains were evaluated by two different methods, including: disc diffusion method, micro-broth dilution assay and
qualitative analysis was performed by gas chromatography-mass spectrometry technique. The peaks potentially
responsible for the antimicrobial activity in essential oils samples were indicated by some linear multivariate
calibration techniques with different preprocessing methods. From the studied techniques, independent component
regression (ICR) was preferred to exhibit the potential antimicrobial active compounds in Satureja hortensis L.
essential oils because of its high repeatability, simplicity and interpretability of the regression coefficients.