studis and antibacterial properties new synthesis complexe with a tridentate Schiff base ligand

Antimicrobial activity of the tested samples was determinedusing a modified Kirby–Bauer disc diffusion method [1]. The antibacterialactivities were done by using gram +ve organisms (Staphylococcusaureus and Bacillus subtillis) and gram -ve organisms(Escherichia coli and Pseudomonas aeruginosa). These bacterialstrains were chosen as they are known human pathogens. Our studies showed that the metal complexes exhibit moderate antibacterial activity, and their antibacterial activity is higher than that of the ligand against both Gram positive and Gram negative bacteria. The studies on Schiff bases have been fast developed because of the wide variety and potential industrial, biological, analytical, medicinal, pharmaceutical and catalytical applications [2-5]. Moreover complexes of Schiff base ligands with some transition metals show significant biological activities, including antimicrobial, antibacterial and anticancer. In view of biological importance of Schiff base derived from the condensation of 2-amino phenol with 5-bromo salicyladehyde and its applications in various fields, in the present investigation we thought it worthwhile to synthesize the complexe. In the present work, we describe the synthesis of new metal complexes with 1-methyl-imidazole and a tridentate Schiff base ligand, obtained by the condensation of H2L .