Catalytic application of {[HIMI]C(CN)3}as a nano molten salt catalyst at the preparation of biologically active hena based compounds

Naphthoquinone derivatives (NQs) are important class of heterocyclic compounds due to their pharmaceutically and biologically activities [1]. In addition, the naphthoquinone subunits are interested as privileged structural motif in the field of medicinal chemistry with numberless bioactivities such as antibacterial fungicidal, antimalarial, trypanocidal, and antitumoralapplicabilities [2]. In this research, we have explored the catalytic performance of 1H-imidazol-3-ium tricyanomethanide {[HIMI]C(CN)3} as a novel, green and efficient catalyst for the preparation of a good range of naphthoquinone derivatives under mild and eco-friendly reaction conditions (Figure1). The scope and limitations of the described procedure will be presented.